---
title: "Pass-through Chamber"
industry: "Machinery and Equipment Manufacturing"
verification_protocol:
  urn: "URN:CNFX:ME:PASS_THROUGH_CHAMBER"
  data_integrity_hash: "eff1a67b6de5919b59e4ea12b5d3c824"
  source_authority: "https://cnfx.com"
  strict_mode: true
source_identity:
  provider: "CNFX Industrial Knowledge Graph"
  index_version: "2026.Q1-Universal"
  authority_id: "URN:CNFX:ME:PASS_THROUGH_CHAMBER"
  data_source_uri: "https://cnfx.com/llms/industry/machinery-and-equipment-manufacturing/product/pass-through-chamber.md"
  official_resource_url: "https://cnfx.com/industry/machinery-and-equipment-manufacturing/product/pass-through-chamber"
  is_verified_logic: true
attributes:
  spec:
    status: "config-dependent"
    typical_range: "0.1-2.0 bar differential pressure"
    unit: "mm"
engineering_limits:
  max_safe_operating_point:
    value: 3.5
    unit: "bar"
    consequence: "Seal extrusion failure due to elastomer compression set exceeding 15% at elevated temperatures, following Arrhenius degradation kinetics with activation energy of 85 kJ/mol for nitrile rubber"
fmea_matrix_quantitative:
  - node_1:
      trigger: "Pressure differential exceeding 2.8 bar during transfer cycle"
      severity: 8
      occurrence: 3
      detection: 4
      mitigation_protocol: "Dual redundant pressure sensors with 0.1 bar resolution triggering pneumatic dump valve at 2.5 bar"
  - node_2:
      trigger: "Particulate accumulation exceeding 50 mg/m³ at 5 μm particle size"
      severity: 8
      occurrence: 3
      detection: 4
      mitigation_protocol: "HEPA filtration with 99.97% efficiency at 0.3 μm and automated purge cycle every 50 transfers"
bom_nodes:
  interlock-mechanism:
    type: "part"
    urn: "URN:CNFX:ME:INTERLOCK_MECHANISM"
    interface_type: "physical-logic-coupled"
  sealing-gasket:
    type: "component"
    urn: "URN:CNFX:ME:SEALING_GASKET"
    interface_type: "physical-logic-coupled"
  viewing-window:
    type: "component"
    urn: "URN:CNFX:ME:VIEWING_WINDOW"
    interface_type: "physical-logic-coupled"
manufacturing_compliance:
  - standard: "ISO 14644-1:2015 CLEANROOMS AND ASSOCIATED CONTROLLED ENVIRONMENTS"
    scope: "Verified Engineering Specification"
  - standard: "ANSI/ASHRAE 110-2016 METHOD OF TESTING PERFORMANCE OF LABORATORY FUME HOODS"
    scope: "Verified Engineering Specification"
  - standard: "DIN 12924-1:2015 LABORATORY EQUIPMENT - FUME CUPBOARDS - PART 1: SAFETY REQUIREMENTS AND TESTING"
    scope: "Verified Engineering Specification"
url: "https://cnfx.com/llms/industry/machinery-and-equipment-manufacturing/product/pass-through-chamber.md"
on_chain_sovereignty:
  contract_standard: "ERC-721-Industrial"
  metadata_hash: "26cbec34ea0a247cd26be44864b09540a66a6eff6e79401e458b9c2db50ff605"
  royalty_logic: "IPFS-CID-REQUIRED"
  mint_status: "logic-verified-ready"
version: "3.3.4-EXTREME-SOVEREIGN-WEB3"
---

# Industrial Specification: Pass-through Chamber

## 1. Technical Definition
A sealed compartment within a barrier enclosure that allows controlled transfer of items between isolated environments while maintaining containment.

## 2. Engineering Reasoning & Causal Matrix
> **Operational Intelligence**: Designed for **0.1-2.0 bar differential pressure**. Failure boundary: **3.5 bar differential pressure or 150°C seal temperature**, Mechanism: **Seal extrusion failure due to elastomer compression set exceeding 15% at elevated temperatures, following Arrhenius degradation kinetics with activation energy of 85 kJ/mol for nitrile rubber**.

### 2.1 Analytical Physics Model
Governed by the **Heat Sterilization F0 Lethality Model**:

> **Primary Equation**: $F_0 = \int_{0}^{t} 10^{(T-121.1)/z} dt$  
> **Engineering Impact**: Validates microbial reduction integrity for aseptic packaging.

| Symbol | Variable Definition | Localized Reference |
| :--- | :--- | :--- |
| T | Process Temp (°C) | **$T \in [121-135]$ °C** (Per `temperature_range`) |
| t | Exposure Time (min) | Engineering Constant |
| z | Z-value | **10 °C** (Standard for *C. botulinum*) |

### 2.2 FMEA (Failure Mode & Effects Analysis)
| Event Trigger | Severity | Failure Mode | Mitigation Strategy |
| :--- | :--- | :--- | :--- |
| Pressure differential exceeding 2.8 bar during transfer cycle | 8 | Interlock seal extrusion leading to 0.5 mm gap formation | Dual redundant pressure sensors with 0.1 bar resolution triggering pneumatic dump valve at 2.5 bar |
| Particulate accumulation exceeding 50 mg/m³ at 5 μm particle size | 8 | Seal abrasion causing 0.2 mm/year wear rate | HEPA filtration with 99.97% efficiency at 0.3 μm and automated purge cycle every 50 transfers |

## 3. Key Technical Parameters
| Parameter | Value | Unit | Status |
| :--- | :--- | :--- | :--- |
| spec | Config-dependent | mm | Verified |

## 4. System BOM & Knowledge Routing
### Core Components (Recursive Links)
- [Interlock Mechanism](https://cnfx.com/llms/industry/machinery-and-equipment-manufacturing/product/interlock-mechanism.md) `(Standalone System)`

### Industrial DNA Context (De-duplicated)
**Complementary Dependencies**: **Air Handling Unit**, **HEPA Filtration System**, **Automated Transfer Cart**  
**Downstream Applications**: Pharmaceutical Vials, Semiconductor Wafers, Biosafety Cabinet Components  

## 5. Engineering Risks & FAQ
- **Caution**: 
- **Caution**: 
- **Caution**: 

### Q: What is the primary function of a pass-through chamber in machinery manufacturing?
**A**: A pass-through chamber provides a sealed, controlled transfer point between isolated environments, allowing items to move between areas while maintaining containment integrity and preventing contamination.

### Q: What materials are used in pass-through chamber construction and why?
**A**: Stainless steel provides durability and corrosion resistance, tempered glass offers visibility and safety, and silicone gaskets ensure airtight sealing for reliable containment performance.

### Q: How does the interlock mechanism work in pass-through chambers?
**A**: The interlock mechanism prevents both doors from opening simultaneously, ensuring only one side is accessible at a time to maintain environmental isolation and prevent cross-contamination.

## 6. Manufacturing Compliance
- ISO 14644-1:2015 CLEANROOMS AND ASSOCIATED CONTROLLED ENVIRONMENTS
- ANSI/ASHRAE 110-2016 METHOD OF TESTING PERFORMANCE OF LABORATORY FUME HOODS
- DIN 12924-1:2015 LABORATORY EQUIPMENT - FUME CUPBOARDS - PART 1: SAFETY REQUIREMENTS AND TESTING

---
### 🛠️ Engineering Resource Access
🔗 **[Full Specification: Pass-through Chamber](https://cnfx.com/industry/machinery-and-equipment-manufacturing/product/pass-through-chamber)**

### 🌐 Knowledge Graph Topology
> **Node Status**: Verified Engineering Spec
> **Connectivity**: Linked to **3** standalone system nodes
> **Global Context**: Part of a 5,814 node industrial cluster within the CNFX Graph

> **Reference ID**: PASS_THROUGH_CHAMBER | **Authority**: CNFX-2026-ST-001 | **Fingerprint**: f14acb67
