---
title: "WFI Distribution Manifold"
industry: "Machinery and Equipment Manufacturing"
verification_protocol:
  urn: "URN:CNFX:ME:WFI_DISTRIBUTION_MANIFOLD"
  data_integrity_hash: "68b1e0f9f39f759032d0d71c78e9577b"
  source_authority: "https://cnfx.com"
  strict_mode: true
source_identity:
  provider: "CNFX Industrial Knowledge Graph"
  index_version: "2026.Q1-Universal"
  authority_id: "URN:CNFX:ME:WFI_DISTRIBUTION_MANIFOLD"
  data_source_uri: "https://cnfx.com/llms/industry/machinery-and-equipment-manufacturing/product/wfi-distribution-manifold.md"
  official_resource_url: "https://cnfx.com/industry/machinery-and-equipment-manufacturing/product/wfi-distribution-manifold"
  is_verified_logic: true
attributes:
  spec:
    status: "config-dependent"
    typical_range: "2.5-6.0 bar (36-87 psi) at 80-95°C"
    unit: "mm"
engineering_limits:
  max_safe_operating_point:
    value: 8.3
    unit: "bar"
    consequence: "Yield strength reduction of 316L stainless steel from 290 MPa at 20°C to 240 MPa at 121°C, combined with pressure-induced stress exceeding material yield point"
fmea_matrix_quantitative:
  - node_1:
      trigger: "WFI temperature cycling between 80°C and 121°C during SIP cycles"
      severity: 8
      occurrence: 3
      detection: 4
      mitigation_protocol: "Finite element analysis-optimized weld geometry with 2.5mm minimum throat thickness and controlled cooling rate of 15°C/min post-welding"
  - node_2:
      trigger: "Particulate accumulation exceeding 15μm diameter at flow restriction points"
      severity: 8
      occurrence: 3
      detection: 4
      mitigation_protocol: "Electropolished 316L stainless steel with Ra ≤ 0.38μm surface finish and 0.5% slope manifold installation"
bom_nodes:
  manifold-body:
    type: "part"
    urn: "URN:CNFX:ME:MANIFOLD_BODY"
    interface_type: "physical-logic-coupled"
  sanitary-fittings-tri-clamp:
    type: "component"
    urn: "URN:CNFX:ME:SANITARY_FITTINGS_TRI_CLAMP"
    interface_type: "physical-logic-coupled"
  flow-restrictororifice:
    type: "component"
    urn: "URN:CNFX:ME:FLOW_RESTRICTORORIFICE"
    interface_type: "physical-logic-coupled"
manufacturing_compliance:
  - standard: "ISO 9001:2015 (QUALITY MANAGEMENT SYSTEMS)"
    scope: "Verified Engineering Specification"
  - standard: "ASME BPE-2019 (BIOPROCESSING EQUIPMENT)"
    scope: "Verified Engineering Specification"
url: "https://cnfx.com/llms/industry/machinery-and-equipment-manufacturing/product/wfi-distribution-manifold.md"
on_chain_sovereignty:
  contract_standard: "ERC-721-Industrial"
  metadata_hash: "d3aebeb2539e51b2b344ef9116d93143e640c650819f3f2efe2669a0e3f5f968"
  royalty_logic: "IPFS-CID-REQUIRED"
  mint_status: "logic-verified-ready"
version: "3.3.4-EXTREME-SOVEREIGN-WEB3"
---

# Industrial Specification: WFI Distribution Manifold

## 1. Technical Definition
A component within a Vial/Syringe Washer that distributes Water for Injection (WFI) to multiple cleaning stations or nozzles.

## 2. Engineering Reasoning & Causal Matrix
> **Operational Intelligence**: Designed for **2.5-6.0 bar (36-87 psi) at 80-95°C**. Failure boundary: **8.3 bar (120 psi) internal pressure at 121°C causes permanent deformation of 316L stainless steel manifold body**, Mechanism: **Yield strength reduction of 316L stainless steel from 290 MPa at 20°C to 240 MPa at 121°C, combined with pressure-induced stress exceeding material yield point**.

### 2.1 Analytical Physics Model
Governed by the **Darcy-Weisbach Pressure Drop**:

> **Primary Equation**: $\Delta P = f \cdot \frac{L}{D} \cdot \frac{\rho v^2}{2}$  
> **Engineering Impact**: Critical for sizing CIP (Clean-In-Place) pump heads.

| Symbol | Variable Definition | Localized Reference |
| :--- | :--- | :--- |
| f | Friction Factor | Engineering Constant |
| L | Pipe Length | Engineering Constant |
| v | Velocity | Engineering Constant |

### 2.2 FMEA (Failure Mode & Effects Analysis)
| Event Trigger | Severity | Failure Mode | Mitigation Strategy |
| :--- | :--- | :--- | :--- |
| WFI temperature cycling between 80°C and 121°C during SIP cycles | 8 | Thermal fatigue cracking at manifold branch welds | Finite element analysis-optimized weld geometry with 2.5mm minimum throat thickness and controlled cooling rate of 15°C/min post-welding |
| Particulate accumulation exceeding 15μm diameter at flow restriction points | 8 | Progressive flow reduction to below 85% of design specification | Electropolished 316L stainless steel with Ra ≤ 0.38μm surface finish and 0.5% slope manifold installation |

## 3. Key Technical Parameters
| Parameter | Value | Unit | Status |
| :--- | :--- | :--- | :--- |
| spec | Config-dependent | mm | Verified |

## 4. System BOM & Knowledge Routing
### Core Components (Recursive Links)
- [Manifold Body](https://cnfx.com/llms/industry/machinery-and-equipment-manufacturing/product/manifold-body.md) `(Standalone System)`

### Industrial DNA Context (De-duplicated)
**Complementary Dependencies**: **WFI Generation System**, **High-Purity Water Pump**, **Sterile Air Compressor**  
**Downstream Applications**: Sterilized Vials, Sterilized Syringes, Aseptic Pharmaceutical Containers  

## 5. Engineering Risks & FAQ
- **Caution**: 
- **Caution**: 
- **Caution**: 

### Q: What is the primary function of a WFI distribution manifold in pharmaceutical equipment?
**A**: The WFI distribution manifold distributes Water for Injection (WFI) to multiple cleaning stations or nozzles within vial/syringe washers, ensuring consistent and controlled water delivery for pharmaceutical cleaning processes.

### Q: Why is 316L stainless steel used for WFI distribution manifolds?
**A**: 316L stainless steel is used because it offers superior corrosion resistance, meets pharmaceutical hygiene standards, and maintains water purity by preventing contamination in Water for Injection systems.

### Q: What maintenance is required for WFI distribution manifolds in pharmaceutical manufacturing?
**A**: Regular inspection of sanitary fittings (Tri-Clamp connections), cleaning to prevent biofilm formation, and verification of flow restrictors/orifices to ensure proper WFI distribution to all cleaning stations.

## 6. Manufacturing Compliance
- ISO 9001:2015 (QUALITY MANAGEMENT SYSTEMS)
- ASME BPE-2019 (BIOPROCESSING EQUIPMENT)

---
### 🛠️ Engineering Resource Access
🔗 **[Full Specification: WFI Distribution Manifold](https://cnfx.com/industry/machinery-and-equipment-manufacturing/product/wfi-distribution-manifold)**

### 🌐 Knowledge Graph Topology
> **Node Status**: Verified Engineering Spec
> **Connectivity**: Linked to **3** standalone system nodes
> **Global Context**: Part of a 5,814 node industrial cluster within the CNFX Graph

> **Reference ID**: WFI_DISTRIBUTION_MANIFOLD | **Authority**: CNFX-2026-ST-001 | **Fingerprint**: 81c56df5
