INDUSTRY COMPONENT

Polypropylene Barrel

Medical-grade polypropylene barrel for syringe applications requiring chemical resistance and biocompatibility.

Component Specifications

Definition
A precision-molded cylindrical component made from medical-grade polypropylene, designed as the main fluid reservoir in disposable syringes. It features graduated volume markings, luer lock or slip tip connections, and smooth internal surfaces to minimize fluid retention. Manufactured under cleanroom conditions to meet pharmaceutical and medical device standards.
Working Principle
Functions as a sterile fluid container where plunger movement creates pressure differentials for accurate liquid aspiration and dispensing. The barrel maintains structural integrity during use while providing clear visibility of contents through transparent or translucent material.
Materials
Medical-grade polypropylene (PP) complying with USP Class VI, ISO 10993, and FDA 21 CFR 177.1520. Typically contains additives for UV stabilization, colorants for coding, and may include radiopaque fillers for X-ray visibility.
Technical Parameters
ParameterTypical rangeNotes & selection driver
Glide Force1-8 N
Length Range30-150 mm
Diameter Range5-50 mm
Surface FinishRa ≤ 0.8 μm
Wall Thickness0.8-2.5 mm
Volume Capacity1-60 mL
Breakloose Force3-15 N
Extractable Volume≤ 3% of nominal volume

Ranges are indicative industry figures for RFQ preparation, not a supplier commitment. Confirm every value and standard with the legal manufacturer before ordering.

Standards
ISO 7886-1, ISO 11040-4, ISO 13485, ASTM D4101, USP <87> <88>

Parent Products

This component is used in the following industrial products

Engineering Analysis

Risks & Mitigation
  • Material degradation from incompatible chemicals
  • Leakage due to poor seal with plunger
  • Graduation inaccuracy affecting dosage
  • Particulate generation during use
  • Biological contamination if sterility compromised
FMEA Triads
Trigger: Inconsistent wall thickness during molding
Failure: Barrel deformation under pressure
Mitigation: Implement statistical process control for injection molding parameters and conduct 100% dimensional inspection
Trigger: Material impurities or contamination
Failure: Chemical leaching affecting drug stability
Mitigation: Use certified medical-grade raw materials with lot traceability and conduct extractables testing per USP <1663>

Industrial Ecosystem

Compatible With

Typical Suppliers & Equivalents

Compliance & Inspection

Tolerance
±2% of nominal volume for graduation accuracy, ±0.1 mm for critical dimensions
Test Method
ISO 7886-1 for sterility, leakage, and force requirements; USP <381> for elastomeric closures; ISO 11040-4 for prefilled syringes

Procurement Evaluation Criteria

A practical evidence checklist for RFQ preparation and supplier evaluation.

Technical documentation
Request current drawings, revision history, and a signed specification sheet.
Manufacturing capability
Verify equipment lists, process limits, capacity, and representative production evidence.
Inspection readiness
Confirm test methods, calibrated equipment, sampling plans, and traceable reports.
Supplier transparency
Check the legal entity, factory address, ownership, certifications, and direct contacts.

CNFX does not score or rank suppliers. Buyers must verify all claims and documents with the legal manufacturer before ordering.

Manufacturers of Polypropylene Barrel

Manufacturer profiles associated with Polypropylene Barrel.

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Frequently Asked Questions

What sterilization methods are compatible with polypropylene syringe barrels?

Medical-grade PP barrels are compatible with ethylene oxide (EtO) gas, gamma radiation, and electron beam sterilization. Autoclaving is generally not recommended as PP may deform at high temperatures.

How are volume graduations applied to syringe barrels?

Graduations are typically molded directly into the barrel surface during injection molding or applied through pad printing with medical-grade inks that withstand sterilization and remain legible throughout shelf life.

Data Basis

Editorial classification, named public sources where available, and source-reviewed manufacturer records. See the editorial policy.

Preliminary Technical Classification
This page supports structured research, RFQ preparation, and supplier evaluation. It does not replace buyer-led supplier qualification, standards review, or technical approval.

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