Industry-Verified Manufacturing Data (2026)

Sealing Flange

Based on aggregated insights from multiple verified factory profiles within the CNFX directory, the standard Sealing Flange used in the Rubber and Plastic Product Manufacturing sector typically supports operational capacities ranging from standard industrial configurations to heavy-duty production requirements.

Technical Definition & Core Assembly

A canonical Sealing Flange is characterized by the integration of Sealing Lip and Compression Zone. In industrial production environments, manufacturers listed on CNFX commonly emphasize Pharmaceutical-grade elastomer (e.g., bromobutyl rubber) construction to support stable, high-cycle operation across diverse manufacturing scenarios.

A specialized flange component designed to create a hermetic seal in pharmaceutical vial rubber stoppers.

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Product Specifications

Technical details and manufacturing context for Sealing Flange

Definition
The sealing flange is a critical component of pharmaceutical vial rubber stoppers that provides the primary sealing interface between the stopper and vial neck. It creates a hermetic barrier to prevent contamination, maintain sterility, and preserve the integrity of pharmaceutical products during storage and transportation.
Working Principle
The sealing flange operates through compression and elastic deformation when the rubber stopper is inserted into the vial neck. The flange's geometry and material properties create radial pressure against the vial's inner surface, forming a tight seal that prevents gas exchange, microbial ingress, and liquid leakage while allowing for needle penetration during administration.
Common Materials
Pharmaceutical-grade elastomer (e.g., bromobutyl rubber), Silicone rubber
Technical Parameters
  • Critical dimensions including outer diameter, inner diameter, flange thickness, and sealing surface geometry that ensure proper fit and sealing performance with standard pharmaceutical vials. (mm) Per Request
Components / BOM
  • Sealing Lip
    Primary contact surface that creates the hermetic seal against the vial
  • Compression Zone
    Area designed to deform elastically during stopper insertion to maintain sealing pressure
  • Transition Section
    Connects the sealing flange to the main stopper body while maintaining structural integrity
Engineering Reasoning
0-3.5 bar differential pressure
4.2 bar differential pressure sustained for >30 seconds
Design Rationale: Elastomer compression set exceeding 15% permanent deformation at 70°C, causing seal interface gap formation >0.05mm
Risk Mitigation (FMEA)
Trigger Autoclave sterilization cycle exceeding 134°C for >18 minutes
Mode: Elastomer cross-link degradation reducing Shore A hardness from 50±5 to <35
Strategy: Integrate PTFE thermal barrier layer with 0.25mm thickness between flange and stopper interface
Trigger Vial filling line vibration at 120Hz resonance frequency with amplitude >0.1mm
Mode: Micro-slip displacement accumulating to 0.3mm radial misalignment over 10,000 cycles
Strategy: Implement hexagonal anti-rotation flange geometry with 0.02mm interference fit tolerance

Industry Taxonomies & Aliases

Commonly used trade names and technical identifiers for Sealing Flange.

pharmaceutical vial rubber stopper sealing flange bromobutyl rubber sealing flange for vials hermetic seal flange pharmaceutical stopper medical-grade silicone rubber sealing component compression zone sealing lip transition section flange

Applied To / Applications

This component is essential for the following industrial systems and equipment:

Optical Access Port
View system integration details

Industrial Ecosystem & Supply Chain DNA

Complementary Systems
Downstream Applications
Specialized Tooling

Application Fit & Sizing Matrix

Operational Limits
pressure: Up to 10 bar (145 psi)
other spec: Flow Rate: N/A (static sealing component), Slurry Concentration: Not applicable for hermetic sealing applications
temperature: -40°C to 150°C
Media Compatibility
✓ Pharmaceutical-grade silicone elastomers ✓ EPDM rubber stoppers ✓ Aqueous injectable solutions
Unsuitable: Organic solvents (e.g., acetone, toluene)
Sizing Data Required
  • Vial neck outer diameter (OD)
  • Stopper compression force requirement
  • Required seal integrity level (e.g., helium leak rate specification)

Reliability & Engineering Risk Analysis

Failure Mode & Root Cause
Gasket compression failure
Cause: Insufficient bolt torque leading to uneven compression and loss of seal integrity
Flange face corrosion/pitting
Cause: Chemical attack from process fluids or environmental exposure compromising sealing surfaces
Maintenance Indicators
  • Visible fluid leakage at flange joint
  • Audible hissing or whistling sound indicating pressure loss
Engineering Tips
  • Implement proper bolt torque sequence and tension monitoring during installation
  • Apply appropriate protective coatings and conduct regular surface inspection for early corrosion detection

Compliance & Manufacturing Standards

Reference Standards
ISO 5211:2017 - Industrial valves - Part-turn actuator attachments ANSI/ASME B16.5:2020 - Pipe Flanges and Flanged Fittings DIN EN 1092-1:2018 - Flanges and their joints - Circular flanges for pipes, valves, fittings and accessories, PN designated
Manufacturing Precision
  • Bore diameter: +/-0.05mm
  • Flatness: 0.08mm across entire sealing surface
Quality Inspection
  • Helium Leak Test for sealing integrity
  • Surface Roughness Test (Ra measurement) on sealing face

Factories Producing Sealing Flange

Verified manufacturers with capability to produce this product in China

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✓ 95% Supplier Capability Match Found

T Technical Director from Brazil Feb 27, 2026
★★★★★
"Standard OEM quality for Rubber and Plastic Product Manufacturing applications. The Sealing Flange arrived with full certification."
Technical Specifications Verified
P Project Engineer from Canada Feb 24, 2026
★★★★☆
"Great transparency on the Sealing Flange components. Essential for our Rubber and Plastic Product Manufacturing supply chain. (Delivery took slightly longer than expected, but technical support was excellent.)"
Technical Specifications Verified
S Sourcing Manager from United States Feb 21, 2026
★★★★★
"The Sealing Flange we sourced perfectly fits our Rubber and Plastic Product Manufacturing production line requirements."
Technical Specifications Verified
Verification Protocol

“Feedback is collected from verified sourcing managers during RFQ (Request for Quote) and factory evaluation processes on CNFX. These reports represent historical performance data and technical audit summaries from our B2B manufacturing network.”

11 sourcing managers are analyzing this specification now. Last inquiry for Sealing Flange from Germany (20m ago).

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Frequently Asked Questions

What materials are used in pharmaceutical sealing flanges?

Our sealing flanges are manufactured using pharmaceutical-grade elastomers such as bromobutyl rubber and silicone rubber, ensuring compatibility with medical applications and maintaining hermetic seals.

How does the three-part BOM design improve sealing performance?

The compression zone applies consistent pressure, the sealing lip creates the primary barrier, and the transition section distributes stress evenly - together ensuring reliable hermetic sealing in vial stoppers.

Are these sealing flanges suitable for sterile pharmaceutical applications?

Yes, these flanges are specifically designed for pharmaceutical vial stoppers, meeting stringent requirements for sterility, chemical resistance, and maintaining hermetic seals in medical packaging.

Can I contact factories directly on CNFX?

CNFX is an open directory, not a transaction platform. Each factory profile provides direct contact information and production details to help you initiate direct inquiries with Chinese suppliers.

Data Specifications verified by CNFX Industrial Index (v2.6.03) for Rubber and Plastic Product Manufacturing sector.

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