This page explains how Depyrogenation Tunnel is classified within Machinery and Equipment Manufacturing. Technical values and manufacturer relationships are research references; confirm the current specification and supplier evidence for each order.
A specialized heating chamber that eliminates pyrogens (endotoxins) from glass vials or containers by exposing them to high temperatures.
Technical details and manufacturing context for Depyrogenation Tunnel
| Parameter | Typical range | Notes & selection driver |
|---|---|---|
| Chamber Length | 3000–12000 mm | Determines throughput; longer tunnels for higher production rates. |
| Belt Width | 400–1200 mm | Matches vial diameter and container footprint. |
| Maximum Temperature | 350–400 °C | Above 400°C may damage glass; below 350°C insufficient depyrogenation. |
| Temperature Uniformity | ±5 °C | Ensures consistent endotoxin inactivation across the belt. |
| Residence Time | 5–30 min | At least 5 min at 300°C for 3-log reduction. |
| Heating Power | 30–150 kW | Depends on tunnel size and required temperature. |
| Air Supply Flow Rate | 1000–8000 m³/h | Provides HEPA-filtered air to maintain cleanliness. |
| Air Pressure Differential | 10–50 Pa | Positive pressure prevents contamination ingress. |
| Electrical Supply | 380–480 V AC | Three-phase, 50/60 Hz. |
| Noise Level | ≤75 dB(A) | Complies with workplace safety regulations. |
| Machine Weight | 3000–15000 kg | Affects installation and floor loading. |
| Footprint (L×W×H) | 4000–15000 × 1500–3000 × 2000–3000 mm | Space required for installation and maintenance. |
Ranges are indicative industry figures for RFQ preparation, not a supplier commitment. Confirm every value and standard with the legal manufacturer before ordering.
| pressure: | Atmospheric to slight negative pressure (0.95-1.05 atm) |
| belt speed: | 0.1-2.0 m/min (adjustable for residence time) |
| temperature: | 250-350°C (typical depyrogenation range) |
| cooling rate: | Controlled cooling to <80°C before discharge |
| heating zones: | 3-5 zones with independent temperature control |
Indicative industry ranges for design and RFQ preparation. Confirm the exact figures and applicable standard with the manufacturer before specifying.
Quoted from the published standard.
Manufacturer profiles associated with Depyrogenation Tunnel.
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A practical evidence checklist for RFQ preparation and supplier evaluation.
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The primary function is to render glass containers, such as vials or ampoules, sterile and pyrogen-free by exposing them to high temperatures (typically 250–350°C) for a validated time. This destroys bacterial endotoxins, ensuring the safety of parenteral drugs.
The maximum temperature range is 350–400°C, with a temperature uniformity of ±5°C. Residence time typically ranges from 5 to 30 minutes, with at least 5 minutes at 300°C for a 3-log reduction in endotoxins.
The tunnel uses HEPA-filtered laminar airflow to maintain cleanliness. Positive air pressure differentials (10–50 Pa) prevent contamination ingress, and the air supply flow rate ranges from 1000 to 8000 m³/h.
Verify model-specific parameters such as chamber length, belt width, heating power, electrical supply, and footprint with the legal manufacturer or supplier. Also confirm compliance with applicable standards and workplace safety regulations, as no specific standards are listed in the source facts.
Editorial classification, named public sources where available, and source-reviewed manufacturer records.
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